A neuroma is a benign tumor of a nerve. Neuromas occur when the tissue surrounding a nerve becomes enlarged and inflamed causing a burning or tingling sensation and cramping in the front of the foot. Tight, poorly-fitting shoes, injury, arthritis, or abnormal bone structure may also cause this condition. Morton’s neuroma is the most common neuroma of the foot and develops when the third and fourth metatarsal bones to pinch together compressing an underlying nerve. It occurs where the nerve passes under the ligament connecting the toe bones (metatarsals) in the forefoot. Neuromas can also occur in other locations. The incidence of Morton’s neuroma is up to 10 times greater in women than in men.